Let the ‘Out-the-Door Price’ Drive Your Next Car Negotiation

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Buying a vehicle is more difficult than ever. Shoppers have long been accustomed to negotiating discounts from the figure on the window sticker. In today’s shortage-driven market, though, many dealers…
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Rewriting History: AI Unravels the Hidden Origins of Papua New Guineans

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Genomic studies show Papua New Guineans are closely related to Asians, shaped by isolation, adaptation, and Denisovan heritage. Papua New Guineans are living proof of how isolation, ancient genetic mixing, and life on remote islands can preserve a distinct chapter of human history. A group of European scientists has recently clarified their genetic origins, applying [...] http://dlvr.it/TMnnzY
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Bitcoin poised to reclaim $90,000, according to derivatives metrics

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Bitcoin (BTC) failed to sustain levels above $85,000 on March 14, despite a 1.9% gain in the S&P 500 index. More importantly, it has been over a week since Bitcoin last traded at $90,000, prompting traders to question whether the bull market is truly over and how long selling pressure will persist. Bitcoin basis rate rebounds from bearish levels From a derivatives perspective, Bitcoin metrics have shown resilience despite a 30% drop from its all-time high of $109,354 on Jan. 20. The Bitcoin basis rate, which measures the premium of monthly contracts over spot markets, has recovered to healthy levels after briefly signaling bearish sentiment on March 13. Bitcoin 2-month futures contracts annualized premium. Source: Laevitas.ch Traders typically demand a 5% to 10% annualized premium to compensate for longer settlement periods. A basis rate below this threshold signals weak demand from leveraged buyers. While the current 5% rate is lower than the 8% recorded two weeks ago, i...
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Google DeepMind’s latest medical breakthrough borrows a trick from AI image generators

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Much of the recent AI hype train has centered around mesmerizing digital content generated from simple prompts, alongside concerns about its ability to decimate the workforce and make malicious propaganda much more convincing. (Fun!) However, some of AI’s most promising — and potentially much less ominous — work lies in medicine. A new update to Google’s AlphaFold software could lead to new disease research and treatment breakthroughs. AlphaFold software, from Google DeepMind and (the also Alphabet-owned) Isomorphic Labs, has already demonstrated that it can predict how proteins fold with shocking accuracy. It’s cataloged a staggering 200 million known proteins, and Google says millions of researchers have used previous versions to make discoveries in areas like malaria vaccines, cancer treatment and enzyme designs.  Knowing a protein’s shape and structure determines how it interacts with the human body, allowing scientists to create new drugs or improve existing ones. But the ne...
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