Controlling the First Steps of Life: Scientists Find New Epigenetic Switch

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In the embryonic development of vertebrates, 5-formylcytosine activates genes. Professor Christof Niehrs and his team at the Institute of Molecular Biology (IMB) in Mainz, Germany, have identified a DNA modification known as 5-formylcytosine (5fC) as an epigenetic switch that activates genes during the early stages of embryonic development. This finding proves for the first time [...]


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